Download torrent Method Development for Analysis of Amphetamine-Type Drugs Using GC-MS
Download torrent Method Development for Analysis of Amphetamine-Type Drugs Using GC-MS

Method Development for Analysis of Amphetamine-Type Drugs Using GC-MS.cSharma Mahesh
Method Development for Analysis of Amphetamine-Type Drugs Using GC-MS
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Author: Sharma Mahesh
Number of Pages: 108 pages
Published Date: 04 Nov 2013
Publisher: LAP Lambert Academic Publishing
Publication Country: United States
Language: English
ISBN: 9783659452673
File size: 42 Mb
File Name: Method.Development.for.Analysis.of.Amphetamine-Type.Drugs.Using.GC-MS.pdf
Download Link: Method Development for Analysis of Amphetamine-Type Drugs Using GC-MS
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Forensic toxicology is the application of toxicology to the matter of law. This work is based on forensic drug testing field of forensic toxicology. Nowadays, the abusing of drugs is considered as a very intense problem which occurring in communities. More and more people are getting addicted to drugs and many are the drug dealers. The main purpose of the present study was the drug profiling and identification of eight Amphetamine-type stimulants (d-amphetamine sulphate, (+)-methamphetamine, Ibuprofen, Piperazine hexahydrate, 1-(4-methoxyphenyl) piperazine, 1-(4-trifluoromethylphenyl) piperazine, 1-Benzylpiperazine and 1-(2-methoxyphenyl) piperazine) by developing a GC-MS method which would detect all the above drugs at the same time. Quinoline was used as internal standard (IS) during the present GC-MS analysis. The first step was the individual drug analysis by the developed GC-MS method and the next step was the mixed drug analysis. The drugs were derivatised by the acylation reagent PFPA, however the silylation reagent BSTFA:TMCS (99:1) was also used as an alternative to acylation. The standard curve of each drug was plotted and the LOD & LOQ was calculated.

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